Ovariectomy and estrogen treatment modulate iron metabolism in rat adipose tissue
نویسندگان
چکیده
منابع مشابه
Estrogen and raloxifene modulate leptin and its receptor in hypothalamus and adipose tissue from ovariectomized rats.
Obesity, from declining estrogen levels after menopause, increases the risk of heart disease, diabetes, and hypertension. Ovariectomy (OVX) in rats is a good model of estrogen insufficiency. The ensuing mild obesity is useful to study how hypoestrogenism alters adiposity. This study examines the hypothesis that in ovariectomized (OVX) rats modification of estrogen levels or treatment with a sel...
متن کاملMetabolism of pyruvate and L-lactate by rat adipose tissue.
The metabolism of r-lactate and pyruvate, labeled uniformly with 14C, by epididymal fat pad tissue of fasted and fasted-refed rats was studied. In tissue of fasted-refed rats, pyruvate and L-lactate were utilized at equal rates. L-Lactate was nearly all converted into CO2 and fatty acids, and pyruvate into COZ, fatty acids, and L-lactate. The incorporation of 14C into glycerol was very low. L-L...
متن کاملAdipose tissue and cholesterol metabolism.
Adipose tissue in man is a major site for cholesterol storage. In obesity over half of total body cholesterol may reside within this tissue; however, relatively little attention has been directed toward understanding the cholesterol metabolism and its relationship to whole body cholesterol homeostasis in this tissue. In this review the factors which influence cholesterol storage are discussed, ...
متن کاملEffects of ovariectomy and estrogen replacement therapy on visceral adipose tissue and serum adiponectin levels in rats.
BACKGROUND Excess visceral adipose tissue accumulation after menopause is closely associated with decreased insulin sensitivity and adiponectin levels. OBJECTIVE The purpose of this study was to determine the effect of ovariectomy and estrogen replacement on visceral fat and serum adiponectin levels in ovariectomized (OVX) rats. METHOD Forty 11-week-old female Wistar rats were divided into ...
متن کاملEffects of Ovariectomy and Estrogen Replacement on Rat Tongue Mucosa
Objective: The aim of this study was to investigate the possible effect of sex steroid deficiency on the rat tongue mucosa as well as the effect of its replacement. Methods: We chose 21 sexually virgin female Wistar albino rats in this study. We divided the model rats into 3 groups: Group-1:Control, Group-2: Sham-operated (bilaterally ovariectomized), and Group-3: Sham-operated, in addition we ...
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ژورنال
عنوان ژورنال: Biochemical Pharmacology
سال: 2009
ISSN: 0006-2952
DOI: 10.1016/j.bcp.2009.05.034